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Company Description

BeyondSpring Inc. is a clinical-stage global biopharmaceutical company. The Company is focused on developing cancer therapies to improve clinical outcomes for patients who have high unmet medical needs. The Company’s lead product Plinabulin, which is being studied as an anti-cancer agent in combination with docetaxel in advanced non-small cell lung cancer (NSCLC). The Plinabulin is a small molecule derived from a natural compound found in marine microorganisms. Its Plinabulin is a selective immunomodulating microtubule-binding agent (SIMBA) with a range of immune activities. Its Plinabulin activates immune defense protein GEF-H1, which leads to two effects: a durable anti-cancer benefits due to the maturation of dendritic cells resulting in activation of tumor antigen-specific T-cells to target cancer cells and early-onset action in chemotherapy-induced neutropenia (CIN) prevention after chemotherapy by boosting the number of hematopoietic stem/progenitor cells (HSPCs).

Drug Pipeline

Source: BeyondSpring Inc - 20220924
Asset
Indication
Phase
Plinabulin
Chemotherapy Induced Neutropenia
Phase 3
 
 
 
 
 
Non-Small Cell Lung Cancer
Phase 3
 
 
 
 
 
Small Cell Lung Cancer
Phase 1
 
 
 
 
 

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